Antiseptic mechanism of nano-sized electrostatic water molecules on SARS-CoV-2

Antiseptic mechanism of nano-sized electrostatic water molecules on SARS-CoV-2

When the envelope, protein, and RNA of SARS-CoV-2 are damaged by small, nano-electrostatic water molecules, the virus is unable to bind to host cells. Credit: University of Warwick

Current disinfection strategies have significant drawbacks, which is why the World Health Organization does not recommend routine spraying or fogging of biocidal agents, or UV sterilization, in occupied areas. One possible alternative is the nano-electrostatic water particles generated by the electrostatic sprayer developed by Panasonic. Water molecules contain reactive oxygen species (ROS) that damage lipids, proteins, and DNA and are said to purify many bacterial and viral species.

Assistant Professor Yasuji’s team showed in their previous research that the electrostatic nanoscale decomposes into atoms water molecules SARS-CoV-2 is cleared, but the mechanism has remained a mystery. Their new paper was published in Journal of Nanoparticle Research Describes the damage they observed when SARS-CoV-2 was exposed to nano-sized electrostatic water molecules.

The researchers showed that the dispersed water particles reduced the infection of cells with SARS-CoV-2 while noting the damage to the virus. “We observed that nano-sized electrostatic water molecules damaged the virus envelope, protein and RNA, rendering them unable to bind to host cells,” explained Associate Professor Yasuji.

“The phenomena we observed are the main mechanism by which small-sized electrostatic water molecules disinfect SARS-CoV-2, and we found that the target of the water molecules is not the specific structure of the viral or specific proteins. Because the water molecules affect the viral envelope, protein and RNA, and may disinfect Other enveloped viral species as well.”

While this proof of concept demonstrates how nano-sized electrostatic water molecules destroy SARS-CoV-2, the full scope of its application remains unclear. “We don’t know exactly what agent destroys SARS-CoV-2; ROS in molecules may be this factor because ROS damage lipid, protein and DNA/RNA through oxidation. Moreover, our studies showed that water molecules purify SARS-CoV.” -2 on surfaces under closed experimental conditions.But the effectiveness of nano-sized electrostatic water molecules can change depending on humidity, temperature, etc. environmental factors; For this method to be practical, it must work in many environments,” Associate Professor Yasuji concluded. Our future studies will focus on the mechanism of action of ROS and test whether electrostatic nano-sized water molecules are effective against airborne SARS. -CoV-2. ”

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more information:
Mayo Yasugi et al., Mechanisms underlying inactivation of SARS-CoV-2 by nano-sized electrostatic water molecules, Journal of Nanoparticle Research (2022). DOI: 10.1007/s11051-022-05485-5

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Osaka University

the quote: Disinfection Mechanism of Electrostatic Nano-sized Water Particles on SARS-CoV-2 (2022, June 17) Retrieved on June 20, 2022 from Electrostatic atomized.html

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